Alan Lloyd Hodgkin

Experimental biologist

1914-1998


Alan Lloyd Hodgkin was an English physiologist and biophysicist who achieved almost complete understanding of excitation and conduction in nerve fibres.

He achieved an almost complete understanding of excitation and conduction in nerve fibres at the level possible with the techniques available at that time, and for this he received a share in the Nobel Prize for Physiology or Medicine in 1963.

The voltage clamp technique is the precursor of the patch clamp in electrophysiology, and is used to bring the internal potential from its resting level and to clamp it at another level for a substantial period. In ByAxon project, the patch clamp technique is used to study the action potential, synaptic activity and single-cell electrical properties in neurons, both in vitro and in vivo.

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